Nature Nanotechnology in 2007, 2: 577-583, it has been cited over 1480 times and has drawn significant attention worldwide. To date, over 130 laboratories across 22 countries have contributed to research on nanozymes. The application of nanozymes has been extended to biology, medicine, agriculture, national defense and many other fields, and has gradually transferred from diagnosis to therapeutics of human diseases. Nanozyme research is an emerging field bridging nanotechnology and biology. By using their multi-functionality, including enzymatic activity and other specific nanoscale properties, nanozymes will likely continue to facilitate the development of state-of-the-art technologies and products to improve human health and quality of life. As we approach the 10-year anniversary of the discovery of nanozymes, I humbly accepted to organize this “nanozyme special edition”. I would like to convey my gratefulness to the editor and all the authors, who have done extraordinary amount of work for their reviews, this project would not have been possible without them.]]> 2018/2/6 0:00:00 YAN Xi-Yun 14true 2018/2/5 0:00:00 DONG Hai-Jiao, ZHANG Chi, FAN Yao-Yao, ZHANG Wei, GU Ning and ZHANG Yu 13true 2018/2/5 0:00:00 TANG Yan, QIU Zhi-Yue, XU Zhuo-Bin and GAO Li-Zeng 12true in vitro applications, which covered the detection of bioactive small molecules, nucleic acids, protein biomarkers, cells, etc. We then discussed the in vivo applications, which included the monitoring of bioactive small molecules in live brains and tumor tissues, the study of drug efficacy, and the investigation of drug and nanozyme metabolism, etc. Finally, we concluded the potential challenges of nanozymes when applying to analytical chemistry and prospected future directions.]]> 2018/2/5 0:00:00 LI Si-Rong, HUANG Yen-Chun, LIU Jia-Rui, WANG Er-Kang and WEI Hui 11true 2018/2/5 0:00:00 Leon Bixenmann, Jiuyang He, Minmin Liang and Wolfgang Tremel 10true 2018/2/5 0:00:00 YANG Rong, CAI Shuang-Fei and WANG Chen 9true 2018/2/5 0:00:00 LI Ai-Peng, YUCHI Qing-Xiao and ZHANG Lian-Bing 8true 3O₄ in 2007 has stimulated the emergence of the new, interdisciplinary research field-nanozymes. Many nanozymes based on metal, metal-oxide, and carbon nanomaterials have been developed, which have applications in the areas of environment, food safety, chemical industry, and biomedicine. Accordingly, progress has also been achieved in the theoretical elucidation of the molecular mechanisms of nanozymes. Here, we will review the basic principles of chemical catalysis. Especially, we will summarize the theoretical results that have been made on the molecular mechanisms of nanozymes consisting of precious metals and carbon materials.]]> 2018/2/5 0:00:00 SHEN Xiao-Mei, GAO Xue-Jiao and GAO Xing-Fa 7true 2018/2/5 0:00:00 MENG Xiang-Qin and FAN Ke-Long 6true 2018/2/5 0:00:00 YANG Bo-Wen, CHEN Yu and SHI Jian-Lin 5true 2018/2/5 0:00:00 HUANG Yan-Yan, LIN You-Hui, PU Fang, REN Jin-Song and QU Xiao-Gang 4true 2018/2/5 0:00:00 MO Wei-Chuan, ZHAO Jing, LIU Ying and HE Rong-Qiao 3true 2018/2/5 0:00:00 LIANG Min-Min and MENG Fan-Xia 2true 2018/2/5 0:00:00 XU Hai-Yan, LIANG Min-Min, ZHANG Yu and WANG Qiang-Bin 1true