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<title cf:type="text"><![CDATA[Progress in Biochemistry and Biophysics -->Interpretation of the Nobel Prize 2020]]></title>
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<title xmlns:cf="http://www.microsoft.com/schemas/rss/core/2005" cf:type="text"><![CDATA[Chemistry Nobel Honors CRISPR-Cas9]]></title>
<link><![CDATA[http://www.pibb.ac.cn/pibben/article/abstract/20200395]]></link>
<description xmlns:cf="http://www.microsoft.com/schemas/rss/core/2005" cf:type="html"><![CDATA[The Nobel Prize in Chemistry 2020 was awarded jointly to Emmanuelle Charpentier and Jennifer A. Doudna "for the development of CRISPR genome editing tool." They have discovered the sharpest tools for gene editing: the CRISPR/Cas9 genetic scissors, which have revolutionary impact on life sciences. The CRISPR system is an adaptive immune system in prokaryotes. Cas9, an effector protein of type II CRISPR-Cas system, functions as a dual-RNA-guided DNA endonuclease, which is able to cleave any dsDNA generating dsDNA break. The CRISPR-Cas9 has been widely used in gene editing, due to its simplicity, high efficiency and low price. This paper introduces the research findings of 2020 Chemistry Nobel Prize winners, summarized the discovery process of CRISPR system and the activity and application of CRISPR-Cas9.]]></description>
<pubDate>2021/3/4 0:00:00</pubDate>
<category><![CDATA[Interpretation of the Nobel Prize 2020]]></category>
<author><![CDATA[YOU Li-Lan,SUN Wei,YANG Xiao-Qi and WANG Yan-Li]]></author>
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<atom:name>YOU Li-Lan,SUN Wei,YANG Xiao-Qi and WANG Yan-Li</atom:name>
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<title xmlns:cf="http://www.microsoft.com/schemas/rss/core/2005" cf:type="text"><![CDATA[The discovery and research progress of Hepatitis C virus-the enlightenment of the Nobel Prize in physiology or Medicine of 2020*]]></title>
<link><![CDATA[http://www.pibb.ac.cn/pibben/article/abstract/20200382]]></link>
<description xmlns:cf="http://www.microsoft.com/schemas/rss/core/2005" cf:type="html"><![CDATA[In 2020, the Nobel Prize in Physiology or Medicine was awarded to Harvey J. Alter, Charles M. Rice and Michael Houghton for their discovery of Hepatitis C virus (HCV). Before the discovery of HCV, the research of Hepatitis A virus and Hepatitis B virus made an important breakthrough. However, a majority of blood-borne hepatitis belongs to non-A, non-B hepatitis, which was discovered as hepatitis C. The discovery of HCV makes blood transfusion safe and makes cure of hepatitis c become possible, saving millions of people’s life. By inducing chronic inflammation and other mechanisms, HCV invade hepatocytes, leading to liver cancer. This paper summarizes the biological characteristics of HCV, systematically expounds mechanisms of HCV infection-associated liver cancer, and introduces measures for prevention and cure of hepatitis c.]]></description>
<pubDate>2021/3/4 0:00:00</pubDate>
<category><![CDATA[Interpretation of the Nobel Prize 2020]]></category>
<author><![CDATA[WU Qi-Wen,ZHOU Rui-Jia,CHEN Shi-Yin,LIU Ling-Yun,ZENG Hong-Li,WANG Fu-Yan,XIONG Wei and ZU Xu-Yu]]></author>
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<atom:name>WU Qi-Wen,ZHOU Rui-Jia,CHEN Shi-Yin,LIU Ling-Yun,ZENG Hong-Li,WANG Fu-Yan,XIONG Wei and ZU Xu-Yu</atom:name>
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