2021/4/2 15:04:00 卫涛涛 5true 2021/4/2 0:00:00 CHEN Siyi,CHEN Ken,YOU Tianhui and SUN Duanping 4true 3O₄ nanoparticles as peroxidase mimics in 2007, a large number of studies on nanoenzymes have continued to emerge. Compared with natural enzymes, nanoenzymes have the advantages such as simple preparation, large-scale production, strong environmental tolerance, low preparation and storage costs, and reusability. Nanohydrolase are nanomaterials with hydrolase activity,and the hydrolase activity of metal organic frame materials, carbon based nanomaterials and gold nanoparticles has been reported. In recent years, the research field of nano hydrolase has entered a booming period, but so far no one has reviewed nanohydrolase. In this review, we first classifies nanohydrolases according to the different substrates and discusses their catalytic mechanisms, then summarizes the factors affecting the activity of nanohydrolases and the application of nanohydrolases, and finally summarizes and discusses the current challenges and future prospects of nanohydrolases.]]> 2021/4/2 0:00:00 XIA Li-Wei,DING Li,CHEN Mao-Long,JIAO Ye,CHENG Yun-Hui and XU Zhou 3true 2021/2/8 0:00:00 CHEN Lu,GAO Xue-Yun and GAO Liang 2true 2021/4/2 0:00:00 WANG Fei,ZHANG Yan and ZHU Li 1true