+T cells, now has been found negatively regulate the differentiation of Th17 cells. In all, differentiation of Th17 and Treg,Th1 cells are exactly regulated in vivo, in which TGF-beta played critical roles. As both Th1 and Th17 cells participate in the pathogenesis of autoimmunity and inflammatory diseases, are they play synergistic roles or function at different time point or location? How TGF-β regulate Th17 and Treg cells？Can Th17 cells be used as a target for immune tolerance induction? All above questions will certainly be of continuing interest.]]> 2008/2/18 0:00:00 HAN Gen-Cheng and SHEN Bei-Fen 4true 2008/2/18 0:00:00 ZHANG Cai and TIAN Zhi-Gang 3true 2008/2/19 0:00:00 ZHAO Jie,YANG Xuan-Ming,DU Pei-Shuang and TANG Hong 2true 2008/2/18 0:00:00 ZHENG Chao-Gu and YAN Xi-Yun 1true