Vol.40,No.3,2013

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Cover Story：The study was aimed to investigate the effects of human bone marrow mesenchymal stem cells (MSCs) in the radiation-induced intestinal injury. MSCs were expanded, labeled with enhance green fluorescentprotein (eGFP). The NOD/SCID mice were randomly assigned to one of three groups: (A) without radiation; (B) and (C) received abdominal radiation with 5 Gy 60Co γ-rays at the rate of 100 cGy/min. (B) i.v. transplanted with physiological saline, (C) i.v. transplanted with MSCs. Mice were weighed daily and observed for 15 days after irradiation. Intestines of mice were obtained in order to assay histological changes by hematoxylin and eosin staining. The immunofluorescence staining showed that the transplanted cells could differentiate into vimentin /α-SMA fibroblastic-like cells in vivo. These data indicated that MSCs could engraft at the injured small intestine, and contribute to the repairment of irradiated intestine. This could provide a valuable strategy for radiation-induced enteritis.

Reviews and Monographs

Crosstalk Between Autophagy and Proteasome SystemsCHEN Ji-Wu,WANG Bang-Zheng,GAO Xiu-Xia and ZHANG Yuan-Yuan  [Abstract][PDF][HTML]

Research Progress of Itch Signal Pathways and Related ReceptorsYANG Yan and TANG Zong-Xiang  [Abstract][PDF][HTML]

ChIP-seq: a New Technique for Genome-wide Profiling of Protein-DNA InteractionLIANG Fang,XU Ke,GONG Zhao-Jian,LI Qiao,MA Jian,XIONG Wei,ZENG Zhao-Yang and LI Gui-Yuan  [Abstract][PDF][HTML]

Short Communications

Post-response Inhibition on Medial Geniculate Neurons in SleepMENG Xian-Kai,SUN Wen-Jian,XU Xin-Xiu,ZHANG Zi-Cong and HE Ju-Fang  [Abstract][PDF][HTML]

Research Papers

Sp100 Interacts With HIV-1 Integrase and Inhibits Viral IntegrationLIN Yun,LI Zhi-Hui,WANG Ran,LI Wen-Juan,WANG Jing-Jing,JI Chao-Neng,XUE Jing-Lun and CHEN Jin-Zhong  [Abstract][PDF][HTML]

Protective Effects of Mesenchymal Stem Cells Against Radiation-induced Intestinal InjuryYANG Chao,ZHANG Xiao-Mei,GONG Yuan,WANG Chang-Zheng,HAN Ying and WU Ben-Yan  [Abstract][PDF][HTML]

Study on The Interactions of Bloom Helicase Catalytic Core With Double-Stranded DNA by Fluorescence Polarization TechnologyLUO Heng,XU Hou-Qiang,CHEN Xiang,LIU Chao-Qian,XU Qing-He and LI Kun  [Abstract][PDF][HTML]

Techniques and Methods

A Novel Method for Assessment of Dynamic Concentration of Exogenous Protein in Serum: an Antibody-independent Sandwich System Based on Avidin-biotin InteractionYU Ying-Xin,LIU Yan-Jun,JIAO De-Long,WEN Li-Yan,XU Jiang-Ping and FU Ning  [Abstract][PDF][HTML]

Establishment of High Performance Liquid Chromatography-Tandem Mass Spectrometry for Intracellular Adenosines Analysis and Its ApplicationsLI Ning,ZHANG Hai-Tao,LUO Hui,ZHANG Liang-Tao,XIONG Yong and JIA Zhen-Bin  [Abstract][PDF][HTML]

New techniques

Label-free Methods in Quantitative ProteomicsWU Peng,HE Fu-Chu and JIANG Ying  [Abstract][PDF][HTML]
©：Progress in Biochemistry and Biophysics
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