Vol.42,No.6,2015

Other Issues:  
  
 
Cover Story:Osteogenesis imperfecta (OI) is a group of rare genetic connective tissue diseases with clinical heterogeneity and genetic heterogeneity. Till now, fifteen subtypes of OI has been identified. Autosomal dominant OI is the primary inheritance pattern, and it is caused by mutations in the COL1A1 or COL1A2 genes that encode the proa1 and proa2. Recessively inherited forms of OI are rare and are caused by mutations in many different genes, which related with post-transcriptional modification, defects of collagen's chaperons and C-propeptide cleavage enzyme, osteoblast/osteocyte differentiation and transcript factor, Ca2+ channel as well as Wnt signaling molecules. The pathogenic genes and mechanisms to dominant and recessive OI are useful for gene detection and individual therapy of OI patients.

Reviews and Monographs

Influenza Virus Assembly and Budding in Lipid RaftsMA Kun, WANG Yu-Juan and WANG Jun-Feng  [Abstract][PDF][HTML]

Asialoglycoprotein Receptor and Its Application in Liver-targeted Drug DeliveryHUANG Yuan-Yu and LIANG Zi-Cai  [Abstract][PDF][HTML]

Molecular Mechanisms of Osteogenesis ImperfectaLU Yan-Qin, REN Xiu-Zhi, WANG Yan-Zhou and HAN Jin-Xiang  [Abstract][PDF][HTML]

Cognitive and Neural Mechanisms of Implied MotionLI Kai-Yun, XU Li-Hui, XUAN Yu-Ming and FU Xiao-Lan  [Abstract][PDF][HTML]

The Research Progress of Nrf2 in Alzheimer′s DiseaseCAO Hui-Min and YU Gang  [Abstract][PDF][HTML]

Structural Dynamics of Live CellsZHANG Xiao-Han and GUO Jun  [Abstract][PDF][HTML]

Short Communications

Mild Prenatal Stress Exposure Contributed to Behavioral Changes Induced by Postnatal Injections and Blocked The Effects of OlanzapineSHAN Liang, LIU Tian-E, ZHAO Xu-Dong and MA Yuan-Ye  [Abstract][PDF][HTML]

Research Papers

Purification and Glycan Profile of Hemagglutinin From Avian Influenza A (H7N2) VirusLI Xue-Tian, SUN Yu, DU Ya-Rong, WANG Xi-Long, ZHANG Pei-Xin, ZHONG Yao-Gang, MA Tian-Ran, WANG Xiu-Rong and LI Zheng  [Abstract][PDF][HTML]

Analysis of Phosphatidylcholines (PCs) and Lysophosphatidylcholines (LysoPCs) in Metastasis of Breast Cancer CellsYOU Jia-Cong, YANG Jie, FANG Run-Ping, HU Nan, ZHANG Xiao-Dong, ZHANG Wei-Ying and YE Li-Hong  [Abstract][PDF][HTML]

Structural Study on Two Tandem Helix Bundles of The ROD Domain of Talin, an Integrin ActivatorLIN Lin, SONG Xian-Qiang, YE Sheng and ZHANG Rong-Guang  [Abstract][PDF][HTML]

Screening and Identification of Genes of Salmonella paratyphi A Related to Anti-phage and Biofilm FormationMAO Pu-Jia, FENG Meng-Die, HONG Yu, XU Ze-Yang, ZHAO Ji-Hua, YANG Hong-Wen, SONG Wu-Zhan, HUANG Fen, JING Shen-Rong and ZENG Wei-Kun  [Abstract][PDF][HTML]

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