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wang yi ming,wang ting,yu ji,zhang shu,tian ning.Boundary deblurring of full-field OCT image of early embryo[J].Progress in Biochemistry and Biophysics
Boundary deblurring of full-field OCT image of early embryo
Received:September 06, 2017  Revised:August 09, 2018
Key words:Optical coherence tomography, noise reduction, early embryo
Fund:国家自然科学基金(11604112),辽宁省自然科学基金(2015020715),沈阳师范大学优秀人才支持计划(BS201433),沈阳师范大学自主科研计划(L201514)和沈阳师范大学博士启动计划(51600209)资助项目
Author NameAffiliationE-mail
wang yi ming College of Physics Science and Technology, Shenyang Normal University 18640553363@163.com 
wang ting College of Physics Science and Technology, Shenyang Normal University  
yu ji College of Physics Science and Technology, Shenyang Normal University  
zhang shu College of Science, Huazhong Agricultural University  
tian ning College of Physics Science and Technology, Shenyang Normal University tiann517@aliyun.com 
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Abstract:
      The full-field optical coherence tomography (FF-OCT) is one of the best technologies to study the morphological development of the early embryo, while its images suffer from some noises. Due to the noises, the boundaries between the different organizations in the early embryo are ambiguous, which would cause interference of organization segmentation. To?solve?this?problem, this paper processed full-field OCT images of early embryos with the median filter, wiener filter and anisotropic diffusion algorithm, and evaluated the noise reduction effect using the signal-to-noise ratio, the mean square error, peak signal to noise ratio and edge retention index. It was shown that early embryo images after noise?reduction with anisotropic diffusion algorithm kept most of the original information with relatively clear boundaries. Therefore, anisotropic diffusion algorithm is suggested to be the best denoising method for FF-OCT imaging in terms of the visual effect.
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