Research: Hyaluronic Acids Protects Against Gastric Infection
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Institute of Biophysics, Chinese Academy of Sciences,Institute of Biophysics, Chinese Academy of Sciences,Bloomage Freda Biopharm Co., Ltd.,Institute of Biophysics, Chinese Academy of Sciences,Institute of Biophysics, Chinese Academy of Sciences

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This work was supported by a grant from Bloomage Freda Biopharm Co., Ltd.

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    Abstract:

    Hyaluronic acid, an important component of extracellular matrix, is up-regulated in intestinal injury to promote wound healing. Here we investigated the roles of hyaluronic acid on different enteritis or intestinal infection models and found that oral administration of hyaluronic acid improved the ability of mice to control the infection of pathogen, including Listeria monocytogenes, Citrobacter rodentium and Enteropathogenic Escherichia coli. These results indicate that hyaluronic acid protects host from gastric infection.

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NIU Jin-Fei, WANG Hai-Fang, FU Jie, PAN Ying, LIU Zhi-Hua.Research: Hyaluronic Acids Protects Against Gastric Infection[J]. Progress in Biochemistry and Biophysics,2018,45(9):981-986

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History
  • Received:July 16,2018
  • Revised:August 13,2018
  • Accepted:August 15,2018
  • Online: September 17,2018
  • Published: September 20,2018