Zhang Wenting,Yao Yufeng.Research Progress on Bacterial DNA Methylation[J].Progress in Biochemistry and Biophysics
Research Progress on Bacterial DNA Methylation
Received:May 04, 2018  Revised:July 07, 2018
Key words:bacteria, DNA, methylation, epigenetic regulation, functions, SMRT
Fund:国家自然科学基金,国家重点基础研究发展计划
Author NameAffiliationE-mail
Zhang Wenting Department of Microbiology and Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University, Shanghai 18829355154@163.com 
Yao Yufeng Department of Microbiology and Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University, Shanghai yfyao@sjtu.edu.cn 
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Abstract:
      DNA methylation is a robust type of gene regulation and plays an important role in physiological processes. This review summarizes the origin of DNA methylation in bacteria, DNA methyltransferases, transcriptional and post-transcriptional regulatory mechanisms by DNA methylation, comments on research progress on DNA methylation functions as well as detection methods. The achievements will be significant for understanding bacterial epigenetic regulation and controlling bacterial infections in the future.
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