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Xiao-Meng Gou,Hong-Liang Sun,Zhong-Guo Zhang,Xin-Yu Xue,Jing-Zhi Hao,Zhang Hong-Sheng.Epigenetic modification of redox regulation in breast cancer[J].Progress in Biochemistry and Biophysics
Epigenetic modification of redox regulation in breast cancer
Received:May 10, 2018  Revised:July 31, 2018
Key words:epigenetic modification  Reactive oxygen species(ROS)  oxidative stress  breast cancer.
Fund:生物大分子国家重点实验室开放课题(2017kf02);2018年国家级大学生创新创业训练计划项目(GJDC-2018-01-52);北京高等学校高水平人才交叉培养“实培计划”(2017271)
Author NameAffiliationE-mail
Xiao-Meng Gou College of Life Science & Bioengineering, Beijing University of Technology 2227827712@qq.com 
Hong-Liang Sun College of Life Science & Bioengineering, Beijing University of Technology  
Zhong-Guo Zhang College of Life Science & Bioengineering, Beijing University of Technology  
Xin-Yu Xue College of Life Science & Bioengineering, Beijing University of Technology  
Jing-Zhi Hao College of Life Science & Bioengineering, Beijing University of Technology  
Zhang Hong-Sheng Beijing University of Technology zhanghs@bjut.edu.cn 
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Abstract:
      Breast cancer is one of the most important malignant tumors affecting women"s health. Epigenetic modification and oxidative stress caused by excessive accumulation of reactive oxygen species (ROS) play a key role in the occurrence and development of breast cancer. In addition, epigenetic modification and the production and clearance of ROS interact with each other. In this paper, epigenetic modification and ROS involved in the occurrence and development of breast cancer are reviewed in order to provide possible ideas for seeking biomarkers and precise therapy for the treatment of breast cancer.
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