Cell Biology is one of the most rapidly developing branches of modern life sciences, characterized by distinct interdisciplinary integration. It provides theoretical foundations, experimental skills, and cutting-edge perspectives for undergraduate and graduate students in bioscience and related majors. Against the backdrop of higher education reform in the new era, the Cell Biology teaching team at the University of Chinese Academy of Sciences (UCAS) has restructured the curriculum. The course focuses on the fundamental structures and life processes of cells while incorporating ideological and political elements to foster students’ scientific mindset, patriotic sentiment, and social responsibility. By optimizing teaching design, enhancing practical components, and innovating assessment methods, the course integrates knowledge transfer, skill development, and value education. This paper summarizes preliminary experiences from the teaching development and educational practice of the undergraduate Cell Biology course at UCAS, serving as a reference for collaborative research- and teaching-oriented courses in science and engineering.