在成玻载体(糖类)和保护剂(分子伴侣和脱水蛋白)存在下,蛋白质类生物活性物质可在室温下被玻璃化.这类玻璃态产品在室温下极其稳定,已被用于可在室温下长期储、运的新一代体外诊断试剂盒的生产.有迹象表明,植物种子的休眠即是由于种子内含有全套成玻物和保护剂,使其所含活性分子能在自然条件下玻璃化而高度稳定.
The glassified proteinaceous bioactive substances are extremely stabilized at room temperature by the presence of the specific carbohydrates as a glass-forming carrier and chaperonins/dehydrins as a protector. There are indications that the natural vitrification of bioactive substances in seed of plant lead the seeds into the dormant phase.
范培昌.蛋白质的玻璃化[J].生物化学与生物物理进展,1999,26(1):5-7
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