主要概述了雄激素受体的作用机制,特别对影响雄激素受体特异性的因素进行探讨.雄激素受体(AR)属于甾体激素受体超家族,能通过配体依赖方式与特异的DNA序列结合,调控基因转录.
The androgen receptor(AR) belongs to the steroid hormone receptor superfamily that is a ligand-dependent transcription factor. It can regulate gene transcription through binding to specific DNA element. The action mechanism of androgen receptors is summarized with a special emphasis on the specificity of the function of androgen receptors.
解芳,刘峻,张永莲.雄激素受体的作用机制[J].生物化学与生物物理进展,1999,26(2):131-134
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