Parkinson disease (PD) is a complex neurodegenerative disorder of the central nervous system（CNS）, the core pathological hallmark of which is the progressive loss of dopamine neurons in the substantia nigra pars compacta. At present, the main treatments of PD include drugs and surgery. However, the drugs lack enough neuroprotective activity, etiological treatment, and are not available in the later period,and the risk of surgery is high. Recently, cellular reprogramming technologies have made breakthrough developments. Induced pluripotent stem cells(iPSCs), induced dopamine neurons(iDNs) and induced neural stem cells(iNSCs) which are generated through reprogramming can be applied to treatment of PD. Transplantation of dopaminergic neurons differentiated from iPSCs, iDNs and iNSCs to specific brain regions can replace the lost neurons or restore the functional integrity of neurons, thus providing an effective treatment for PD. This article introduces mechanisms of cellular reprogramming, and summarizes advantages, disadvantages and efficacy of iPSCs, iDNs and iNSCs in the treatment of PD. It also explains current challenges and discusses the possible solutions.