Objective Magnetically-coupled resonant wireless power transfer (MCR-WPT) has the advantages of large transmission distance, high transmission efficiency and penetration, which brings convenience to people’s lives. However, the safety of bioelectromagnetic effects caused by MCR-WPT has attracted much attention. In this paper, the influence of MCR-WPT electromagnetic environment on the characteristics of neuronal K⁺ channels in the dentate gyrus (DG) region of the mouse hippocampus was studied, in order to provide an experimental basis for the development and rational development and application of WPT technology.Methods Mice were continuously irradiated for 5 h for 30 d, and the learning and memory ability, instantaneous outward K⁺ channel current (I_A) and delayed rectification K⁺ channel current (I_K) of neurons in the hippocampal DG region were compared and analyzed by the control group and the magnetic field exposure groups of 5 d, 15 d and 30 d.Results The activation process of transient outward potassium channels in the magnetic field exposure group was inhibited, and the activation characteristics of delayed rectified potassium channels shifted to the depolarization direction, which reduced the outflow of K⁺ and enhanced the nerve excitability, but there was no significant change in the behavior of the magnetic field exposed group mice.Conclusion Long-term exposure to the electromagnetic environment of MCR-WPT altered the I-V properties and kinetic properties of K⁺ ion channels, inhibited I_A and I_K, and changed the frequency of neuronal action potential issuance, but these changes did not cause a decrease in learning memory capacity and cognitive dysfunction in mice.