MK是一种新发现的细胞因子,属于肝素结合因子家族,MK是一种小分子多肽,其基因表达仅见于胚胎中期及成年期肾脏,在许多肿瘤细胞中也可见MK基因不同程度的表达,MK能够促进正常细胞的生长和分化,特别是促进神经细胞的发育,它还可以抑制某些肿瘤细胞的生长.MK基因在成年肾脏中表达的原因尚未阐明.
MK is a new identified cytokine, which belongs to the heparin binding family. MK molecule is a small polypeptide whose gene expresses only in mid-gestation embryo and adult kidney.The expression of MK gene has also been shown in various carcinoma cells. MK can promote the growth and differentiation of normal cells,particularly the development of nerve cells.MK can also inhibit the growth of several kinds of carcinoma cells.The reason why MK gene is expressed in adult kidney has not been elucidated.
齐茂松,李春英. MK──一种新发现的细胞因子[J].生物化学与生物物理进展,1995,22(3):214-216
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