白细胞介素一15是一种最近被正式承认的新细胞因子,该因子cDNA结构和功能及分子结构已阐明,其生物学活性和空间构象与IL-2非常相似但又有差异,IL-15受体至少包括IL-2受体β和γ链亚单位,是否尚有其他未知成分参与IL-15受体的组成和其详细的信号传递途径以及其他未知生物学活性如何尚有待深入研究.
Interleukin-15 is a kind of formally recognized new cytokine, its cDNA sequence,function and molecular structure have been elucidated. IL-15 is similar to IL-2 in biological properties and three-dimensional configuration and its receptor utilizes the β and γchains of IL-2 receptor. Further investigation should be done on whether other unknown components participate in IL-15 receptor complexes, its detailed signaling pathway and other unknown biological activities etc.
蔡铀庆.白细胞介素-15研究进展[J].生物化学与生物物理进展,1996,23(1):2-4
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