Heat shock induced significant increase of the SOD and CAT activities in silkworm of various ages, such as at 40℃ the induced SOD activity was maximal, where both the activities of CuZn-SOD and MnSOD were also increased. Alter exposure at 36℃ for 1h,GSH-Px activity was decreased, but it was increased at 40℃. Among the different regions of silkworm, the activities of SOD and CAT have great diversities in the order of priorities:thoracicoabdominal region, head region,posterior silkgland. Heat shock also had different influences on the activities of the antioxidative enzymes of different regions to adapt different physiological states of silkworm. The antioxidases work cooperative interaction, so that the normal physiological functions are maintained.