丝氨酸蛋白酶抑制剂(serpin)是一类结构、序列同源的蛋白酶抑制剂,它是体内许多蛋白水解级联反应的调节因子,其遗传性结构或分泌异常将导致许多疾病.因此对于其结构及作用机理的研究将为临床应用提供依据.
Serpin is a family of serine proteinase inhibitors homologous in structure and sequence,regulating many proteolysis cascade reactions.Their genetic aberrations in structure or secretion may result in substantial pathological problems. The clinical applications are based on their structures and mechanisms of inhibition.
张梅,朱柞铭.丝氨酸蛋白酶抑制剂的研究及应用[J].生物化学与生物物理进展,1996,23(3):240-244
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