After the fusion between the C₆₀-phosphatidylcholine liposome (C₆₀-concentration as 20 mg/L) and HeLa cells and illumination with the Tungsten-Halogen lamp (4 000 lx, 30 min), the most of cells were killed by the evaluation of MTT assay (3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide). Biochemical test showed that photoexcited C₆₀ led to the decrease of the sulfhydryl content of the membrane protein and the increase of the malonidaldehyde (MDA) with the peroxidation of the membrane lipid. SDS-PAGE showed the conjugation of the membrane protein. Fluorescence polarization (FP) indicated that the fluidity of the cell membrane increase.