Using the pulse microprogram edited 2D ¹H-¹⁵N HSQC, HSQC-NOESY, HSQC-TOCSY spectra of the ¹⁵N-labeled protein GAL4(62) were abtained, while solvent suppression was achieved by presaturation during the relaxation delay and by the use of spin-lock purge pulses. The important role of those 2D experiments in ¹H assignments of ¹⁵N-labeled proteins was discussed.