国家自然科学基金(39670235、39770409、39770238)和863计划生物领域青年基金资助课题.
DNA损伤和损伤后修复可引起细胞周期阻滞,这一事件由三个阶段组成:损伤的识别,损伤信号的传递以及细胞周期阻滞.在某些情况,这种细胞周期阻滞会失效.
DNA damage and repair of damaged DNA can cause cell cycle arrest. This process is consisted of three periods: recognition of damage domain in the DNA, transduction of damage signal and cell cycle arrest. Sometimes, this kind of cell cycle arrest may be failed.
于廷曦,朱应葆,童坦君. DNA损伤与细胞周期调控[J].生物化学与生物物理进展,1999,26(4):351-354
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