国家自然科学基金资助项目(39710106,39670186和69835002).
视觉研究对于揭示大脑的奥秘有着极其重要的意义.功能性磁共振成像(functional magnetic resonance imaging,fMRI)用于研究人脑的功能结构,主要是基于静脉毛细血管内血氧浓度的变化.fMRI可以无损伤地在几毫米级的空间分辨率和少于1 s的时间分辨率上观察清醒状态下人脑的活动,因此自90年代以来fMRI已经成为研究人脑的重要方法.fMRI在视觉研究中的应用已经使人们对视觉系统的功能性组织有了更好的理解,并取得了很多成果.今后的研究方向是进一步探讨人脑的意识、注意、记忆等高级功能的神经机制.
Vision research is very important to reveal the mystery of brain. Functional magnetic resonance imaging(fMRI) is a method for measuring hemodynamic responses to changes in neural activity in the brain. As the activity in the human brain can be observed by fMRI non-invasively with spatial resolution of a few millimeters and temporal resolution of less than a second, fMRI has become an important approach to human brain research since the 1990s. The recent application of fMRI to visual studies has begun to elucidate how the human visual system is anatomically and functionally organized. There is much more work to do to investigate the neural mechanism of the higher-level functions such as mind、attention and memory.
倪睿,吴新年,齐翔林,汪云九. fMRI在视觉研究中的应用和进展[J].生物化学与生物物理进展,2000,27(3):254-257
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