分子发动机是利用化学能/化学势进行机械作功的生物大分子,包括线性分子发动机与旋转式分子发动机两大类.它们参与了胞质运输、DNA复制、基因转录、ATP合成/水解等一系列重要生命活动过程.目前对于各种分子发动机的结构及作用机制的研究取得了一些重要进展.
Molecular motors are the proteins that translate the free energy/electrochemical gradient into mechanical work. They are generally divided into two classes: one is linear motor, including myosin, kinesin, dynesin, RNA polymerase and DNA helicase, the other is rotary motor, such as F1-ATPase and the bacterial flagellar motor. The molecular motors play an important role in the cell transport,DNA replication, transcription, and ATP synthesis.
王宏斌,王金发.分子发动机研究进展[J].生物化学与生物物理进展,2000,27(3):265-269
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