College of Life Science and Bioengineering, Beijing University of Technology,College of Science, Yanshan University,College of Life Science and Bioengineering, Beijing University of Technology,College of Life Science and Bioengineering, Beijing University of Technology,Biophysics and Nanoscience Centre,Dipartimento di Ecologia e Biologia DEB Universita’ della Tuscia, Viterbo,Italy,Biophysics and Nanoscience Centre,Dipartimento di Ecologia e Biologia DEB Universita’ della Tuscia, Viterbo,Italy

This work was supported by grants from International S&T Cooperation Program of China (2010DFA31710), The National Natural Science Foundation of China (11204267), The doctoral fund of innovation from Beijing University of Technology and by a grant from The Italian Association for Cancer Research (AIRC No IG 10412)