Advances in sequencing technology have led to a sharp decrease in the cost and rapid increase in the speed of sequencing an entire human genome. It has become one of the most important issues to analyze and visualize genome sequence in life science field. Genome browser technology plays important roles in analyzing genome sequence, interpreting genetic codes, studying complex diseases and so on. In this paper, we review the nine major genome browser technologies and analyze their characteristics in visualized content, visible form, software system architecture and so on. Finally, we discuss the challenges that genome browser faced.