The various methods to make supported bilayer systems on solid substrates are straight foreward.Comparing with liposomes and other systems,these systems have the advantages of better reproducibility,tighter controls over their physicochemical properties.Since membrane proteins can be incorporated into these supported bilayers, they are ideal model systems in the studies of biomembranes. Along with the improvements in the investigation methods,studies on these membranous systems are progressing into deeper details and there have appeared more applications of these model systems in biological and medical researches. The producing and studying methods of surpported bilayer systems on solid substrate are reviewed，and some examples of successful applications of these systems in membrane biophysical chemistry are attempted to give.