The Structure-Function Relaationship and the Signal Transduction Pathway of Ras Protein
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    Abstract:

    The ras gene has attracted great attention ever since it has been discovered having a relationship to cancer.Scientists not only know nowadays the mechanism about how ras gene results in cancer but also have a clear understanding about the relationship between Ras protein and the pathway of phosphorylation.In addition,the research about the signal transduction pathway which has something to do with the Ras protein leads to a more detailed understanding about the regulation of information communication in cells. Further more,the signal transduction pathways of Ras and of other proteins interact with each other. For example,the Ras pathway can be activated by the αβ dimer of G protein. Therefore,it is extremely necessary to study the Ras pathway,which will throw great insight on the regulation of Ras itself and the signal transduction on the cell level.

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Xiong Shunbin, Tang Chaoyu, Xu Genjun. The Structure-Function Relaationship and the Signal Transduction Pathway of Ras Protein[J]. Progress in Biochemistry and Biophysics,1995,22(6):482-486

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History
  • Received:November 24,1994
  • Revised:March 16,1995
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