The following studies on molecular biology of scorpion toxin genes were reviewed:(1) Strategies of cloning cDNAs or genomic genes encoding scorpion toxins;(2) scorpion toxin cDNAs and post-protein processing of precursor toxins;(3)Structural organization and pre-mRNA processing of genomic genes encoding scorpion toxins;(4)Expression of recombinant scorpion toxin genes in cells or organisms.