DNA damage and repair of damaged DNA can cause cell cycle arrest. This process is consisted of three periods: recognition of damage domain in the DNA, transduction of damage signal and cell cycle arrest. Sometimes, this kind of cell cycle arrest may be failed.
YU Ting-Xi, ZHU Ying-Bao, TONG Tan-Jun. DNA Damage and Cell Cycle Control[J]. Progress in Biochemistry and Biophysics,1999,26(4):351-354
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