In order to study function of the cortical nociceptive neurons(NCNs) on the cell level with intracellular recording and stereotaxic techniques,the electrical properties of their memberane were studied.The frequency of spontaneous discharges of the neurons were diverse obviously and revealed a variety of mode in discharge. When absolute value of polarization current was lesser than 1.0 nA,the relation of I-V in NCNs was more significant(r=0.96) and the rectification insignificant;when the polarization current larger than 1.0 nA, the rectification occurred on both ends of the curve and then I-V curve showed S-type. The rectification of somatic NCNs was much significant than non-nociceptive ones(NNCNs). R_m,τ and C_m of the NCNs were evidently larger than those of NNCNs(P＜0.01 or P＜0.05).The materials obtained indicated that morphology and structural of cell membrane,volume of the soma bettween NCNs and NNCNs might have meaningful differences. It also means that physiological functions were unlike. The specificity of the electrical parameters in cell membrane might provide experimental materials for specific theory of pain sensation. Reporting to investigate electrical properties(R_m,τ and C_m) of the membrane in primary cortial nociceptive neurons had not found in literatures.