Photocatalytic titanium apatite filter (PTAF) is a new material that has been reported to have an ability to absorb and inactivate bacteria. The inactivation effect of PTAF on serious acute respiratory syndrome coronary virus (SARS-CoV) was tested. The results showed that PTAF filter inactivated/decomposed SARS CoV up to 99.99％ after 6 h interaction under the condition of non-UV irradiation. However, under the condition of UV irradiation, PTAF and HAF both were able to inactivate/decompose SARS CoV completely. The study has provided the first evidences that PTAF could inactivate SARS-CoV virus, suggesting that the PTAF material will be applied for the prevention of SARS-CoV as well as other viruses.