Proximity and similarity organization are two extremely important kinds of perceptual organization. In this study, a patient with anterior-temporal lobe damage CXY took part in our proximity and similarity experiments. In this study, compound stimuli that a global figure made up of local figures were used to investigate the interference of global and local in the proximity and similarity perceptual organization. In the global-local experiment, we found that, normal subjects showed stronger global interference than local interference in the proximity perceptual organization. Such effect, however, disappeared in CXY, suggesting there was an obstacle in his automatic processing of the proximity organization; in similarity organization, there was no difference between CXY and normal subjects. In the uniform connectedness experiment, we also found the obstacle in CXY's automatic processing of the proximity organization. These results indicated that the anterior-temporal lobe plays an important role in proximity organization, global organization and uniform connectedness.