CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences;CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences;CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences;CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences;CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences;CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences;CAS Key Laboratory of Health Informatics,Guangdong Key Laboratory of Nanomedicine,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences

This work was supported by grants from The National Natural Science Foundation of China (81071249, 81171446, 20905050), Guangdong Innovation Team of Low-cost Healthcare, Science and Technology Key Project of Shenzhen (CXB201005250029A, JC201005260247A), and The ''Hundred Talents Program'' of Chinese Academy of Sciences (SY29064)