Key Laboratory of Advanced Technologies of Materials, School of Materials Science and Engineering, Southwest Jiaotong University,Key Laboratory of Advanced Technologies of Materials, School of Materials Science and Engineering, Southwest Jiaotong University,Key Laboratory of Advanced Technologies of Materials, School of Materials Science and Engineering, Southwest Jiaotong University,Key Laboratory of Advanced Technologies of Materials, School of Materials Science and Engineering, Southwest Jiaotong University,Key Laboratory of Advanced Technologies of Materials, School of Materials Science and Engineering, Southwest Jiaotong University,Key Laboratory of Advanced Technologies of Materials, School of Materials Science and Engineering, Southwest Jiaotong University
This work was supported by grants from National Basic Research Program of China (2012CB933602), The National Natural Science Foundation of China (51172188), Science and Technology Pillar Project of Sichuan (2010FZ0048), Fundamental Research Funds for Central Universities (SWJTU11ZT11), Youth Science and Technology Foundation of Innovative Team Project of Sichuan (2010JQ0081) and the 2013 Doctoral Innovation Funds of SWJTU
As a main inorganic component of the human bone, hydroxyapatite (HA) is widely used in hard tissue repair and replacement. With high surface area and excellent fluidity, HA microspheres have gained extensive interests for biomedical applications. This article reviews the synthesis of HA microspheres with nanostructures, with a special focus on the use of soft and hard templates. The formation mechanism of these microspheres and related nanostructures are also discussed in detail. Problems in current synthesis methods are identified and the future trends of this emerging field are also discussed.
XIAO Dong-Qin, CHI Feng, YAO Ning, ZHANG Cheng-Dong, DUAN Ke, WENG Jie.Review: Nanostructured Hydroxyapatite Microspheres by Templated Synthesis:Formation and Mechanisms[J]. Progress in Biochemistry and Biophysics,2013,40(10):935-947
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