Jiangsu Key Laboratory of Experimental Translational Non-coding RNA Research,Institute of Translational Medicine,School of Medicine,Yangzhou University. 11 Huaihai Road,Yangzhou,Jiangsu Key Laboratory of Experimental Translational Non-coding RNA Research,Institute of Translational Medicine,School of Medicine,Yangzhou University. 11 Huaihai Road,Yangzhou,Jiangsu Key Laboratory of Experimental Translational Non-coding RNA Research,Institute of Translational Medicine,School of Medicine,Yangzhou University. 11 Huaihai Road,Yangzhou,Jiangsu Key Laboratory of Experimental Translational Non-coding RNA Research,Institute of Translational Medicine,School of Medicine,Yangzhou University. 11 Huaihai Road,Yangzhou
This work was supported by grants from The National Natural Science Foundation of China (81671810) and The Basic Research Project of Natural Science Foundation of Jiangsu Province (BK20161333)
Antibiotic-resistance of bacteria and antibiotics abuse is a global challenge. It is urgent to develop novel bactericide alternative to kill bacteria efficiently but without causing new resistance and biosafety issue. Nanozymes are nanomaterials with intrinsic enzyme-like activities which regulate reactive oxygen species (ROS) by redox reactions. This property can be used to suppress many gram-positive and gram-negative virulent bacteria and biofilms. Meanwhile, nanozymes have high stability, biocompatibility and reusability compared to other biocidal agents. Therefore nanozymes present a promising antibacterial alternative in the application of wound healing, caries prevention and marine antifouling.
TANG Yan, QIU Zhi-Yue, XU Zhuo-Bin, GAO Li-Zeng.Reviews and Monographs: Antibacterial Mechanism and Applications of Nanozymes[J]. Progress in Biochemistry and Biophysics,2018,45(2):118-128
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