Caloric restriction (CR) refers to a 20%－40% reduction in caloric intake without reducing essential nutrient intake. CR can alleviate the cardiovascular aging process under physiological and pathological conditions by mainly mechanisms including oxidative stress, inflammation, programmed death and telomerewhich are mediated by sundry molecules as well as regulating the risk factors of cardiovascular aging in human and other animals. This paper systematically elaborates the research progress of CR and cardiovascular aging and explore the solution to prevent cardiovascular aging in humans.