The CC chemokines is the largest and most widely studied group of chemokines,which play a critical role in inflammatory leukocyte locomotion ,trafficking and adhesion. The chemokine cc subfamily are involed in the pathogenesis of myocardial infarction. Monocyte chemoattractant protein-1 (MCP-1) and its receptor CC Chemokine receptor 2 (CCR2) ,as most-study chemokine,play an important role in post-infarction inflammation, proliferation and scar formation, thus affecting ventricular remodeling after myocardial infarction.In recent years, other members of the CC chemokines have been gradually revealed to be involved in the development of myocardial infarction. This article reviews the role of CC chemokines in various stages of myocardial infarction, especially the effects on ventricular remodeling after myocardial infarction, in order to provide direction for future experimental research and novel strategies in the treatment of patients with myocardial infarction disease.