Automatic Diagnosis of Vaginal Microecological Pathological Images Based on Deep Learning
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1)College of Computer, National University of Defense Technology, Changsha 410073, China;2)Computer Network Information Center, Chinese Academy of Sciences, Beijing 100850, China

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This work was supported by grants from National Key Research and Development Program of China (2018YFB0204301), The National Natural Science Foundation of China (81973244) and State Key Laboratory of High Perfomance Computing, National University of Defense Technology.

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    Abstract:

    Vaginal microflora pathological image is an important basis for the diagnosis of bacterial vaginosis, but analysis of the images manually takes a lot of time and effort, leading to low diagnosis efficiency, so new methods of automatic pathological image diagnosis need to be sought. In this paper, we proposed a model, ResLab, to diagnose vaginal microflora pathological image automatically. It took the pathological reports of gynecological examination as training set, and used deep learning technology to perform end-to-end analysis on the pathological images. The ResLab model predicted Nugent score to assist doctors in grading diagnosis. We optimized the ResLab in multiple ways to improve the prediction accuracy, by increasing the number of layers to extract deeper features, stacking two small convolution kernels to increase the receptive field, removing ReLU layers to reduce complexity, and replacing average pooling layer with max pooling layer to extract the most salient feature. It was proven that each optimization plan can significantly improve the perfomance of the model. The prediction accuracy of the ResLab model reached 82.19%, which outperformed VGG, GoogLeNet, ResNet. The ResLab model can provide doctors with relatively accurate reference results, thereby improving diagnosis efficiency and reducing diagnostic error.

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YAO Ze-Huan, CHEN Wei, LI Chen, YANG Hao-Yi, HE Yu-Lin, TAN Yu-Song, LI Fei. Automatic Diagnosis of Vaginal Microecological Pathological Images Based on Deep Learning[J]. Progress in Biochemistry and Biophysics,2021,48(11):1348-1357

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History
  • Received:March 11,2021
  • Revised:June 23,2021
  • Accepted:July 05,2021
  • Online: November 23,2021
  • Published: November 20,2021