叙述了真核细胞三种RNA聚合酶合成的基因的转录调控.由于真核细胞DNA含量非常大,其基因的转录调控具有以下特点:参与的转录因子多;与顺式DNA序列元件结合呈一定顺序.这反映了真核细胞中基因的转录调控是由多个转录因子间的相互作用来实现的.
This review summarizes the transcriptional regulations in the eucaryotic genes transcriped by three kinds of RNA polymerases. The regulatory strategies differ for higher eucaryotic cells with their huge DNA contents. First. much greater numbers of transcriptional factors are required. And second, these regulatory proteins simultaneously bind ot the nearby specific sites on DNA with proper orders. This demonstrated that the control of transcription in eucaryotic cells involves the interaction of protein factors with specific DNA sequence elements and the interactions between protein factors.
胡美浩.真核细胞中基因的转录调控[J].生物化学与生物物理进展,1994,21(2):117-122
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