Cytoplasmic free Ca2+ and Mg2+ concentration(c (Ca2+)i and c(Mg2+)i) of alveolar macrophages in rabbit lung after incubation with sodium selenite were determined by SPEX AR-CM-MIC system.The results showed that high concentration sodium selenite(≥10-4mol/L) had the cytotoxicity.The poisonous effect of selenite on macrophage led to the increase of c(Ca2+)i and c(Mg2+)i.High concentration selenite had some suppressive effect on the Ca2+-ATPase activity of erythrocyte membrane.
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