A 29 ku protein, the sensory nerve-specific protein was isolated and purified from rabbit spinal ganglion and its fibers by anion exchange chromatography using DEAE-Sephacel and gel filtration HPLC. The purity was extiomatd to be over 80% by UV scanning. Western blot demonstrated that it immunoreacts with anti-rabbit the 29 ku protein monoclonal antibody. The stability also has been observed.