Mitochondria are important organelles for eukaryotic energy metabolism and are the main sites for oxidative phosphorylation of cells to produce ATP.It participates in the physiological functions of cell energy metabolism,maintaining ion concentration gradient,and transmitting apoptosis signals.Diseases such as Alzheimer disease,Parkinson disease,and myocardial infarction are associated with mitochondrial dysfunction. In recent years,it has been found that mitochondrial transfer occurs between cells in the brain,heart,and lung during hypoxia caused by trauma or inflammation.Intercellular mitochondrial transfer,as an evolutionarily conserved phenomenon,may be associated with neurodegradation,cardiovascular disease,and the like.