The intracellular microelectrode recording technique, channel blocker and radioisotope tracer method were used. The burst discharges were evoked by Zn2+, no change by sodium channel blocker——Tetrodotoxin, but abolished by calcium channel blocker——Cd2+. [65Zn2+]i was decreased by Cd2+. It is possible, that Zn2+, instead of Ca2+, goes into cells through calcium channels in the mechanism of BD evoked by Zn2+.
Wu Benjie, Zhang Chuanli. THE INFLUENCE OF TETRODOTOXIN AND Cd2+ ON BURST DISCHARGES EVOKED BY Zn2+[J]. Progress in Biochemistry and Biophysics,1990,17(2):117-120
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