The lactose lectins we used in this experiment were extracted from chicken embryo tissues using lactose and urea method. They were further purified with DE-52 cellulose ion exchange chromatography and Dextran Blue-Sepharose 4B affinity chromatography. The purified embryo liver lectin was labeled with ¹²⁵I and its specific radioactivity was 8.6μci/μg. We have utilized the autoradiography combined with scanning electro microscope(SEM-ARG) to observe the lectin receptors on liver cells, kidney ceils and rabbit red cells. The developed silver grains could be seen clearly on these cell surfaces. The silver grains represent the lectin receptor sites on cell surfaces. We found that the grains on liver cells were more than those on cells from other tissues. This result is consistent with the result which has been performed by the experiment of the specificity of chicken lactose lectin. Therefore,it is suggested that the chicken embryo liver lectin has certain specificity.