Day-night variation of the content of CREB in the suprachiasmatic nucleus was analyzed in male Wistar rats maintained under light-dark cycles and constant dark by gel-mobility shift.It was found that the CREB in the SCN has endogeneous circadian rhythm.
Yang Jing, Chen Hong, Inouye S. I. T. Circadian Rhythm of CREB in the Rat Suprachiasmatic Nucleus[J]. Progress in Biochemistry and Biophysics,1995,22(2):181-183
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