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Effects of Sodium Selenite on Cytoplasmic Free Ca2+ and Mg2+ of Alveolar Macrophages
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    Abstract:

    Cytoplasmic free Ca2+ and Mg2+ concentration(c (Ca2+)i and c(Mg2+)i) of alveolar macrophages in rabbit lung after incubation with sodium selenite were determined by SPEX AR-CM-MIC system.The results showed that high concentration sodium selenite(≥10-4mol/L) had the cytotoxicity.The poisonous effect of selenite on macrophage led to the increase of c(Ca2+)i and c(Mg2+)i.High concentration selenite had some suppressive effect on the Ca2+-ATPase activity of erythrocyte membrane.

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Wen Herui, Wang Jinxi, Zhu Weihua, Li Ruiyan, Chen Rongsan. Effects of Sodium Selenite on Cytoplasmic Free Ca2+ and Mg2+ of Alveolar Macrophages[J]. Progress in Biochemistry and Biophysics,1995,22(6):526-529

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History
  • Received:November 29,1994
  • Revised:July 05,1995
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