Many checkpoint genes and proteins have been screened from different species and cells until now, such as ATM, RAD53, CHK1 etc. There are a lot of reports about their function in checkpoint control pathways as well as the correspondances with cancers.
ZHANG Ping-bo, HONG Xi-jun, LIU Yan. Progress in the Studies of Checkpoint Control Pathways of Cell Cycle[J]. Progress in Biochemistry and Biophysics,1998,25(2):110-114
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