With the development of biochip techniques, several new types of biochip, such as bioelectronic chip, gel element microarray chip, drug controlled-release chip, capillary eletrophoretic or electrochromatographic chip, PCR chip and biosensor chip, had sprung up. These biochips, which were different from typical molecular microarrays such as DNA chip, were based on the microarray of various structures, and have successfully applied to analyze DNA mutations, polymorphisms and sequences, to separate mixtures and monitor biomolecular interactions. Because analyses on these chips have many advantages such as quick detection, high efficiency, little sample consumed and low cost, they will become novel tools in the field of life science and medicine.
XU Bing-Sen, SHAO Jian-Zhong. Advancement of Several New Types of Biochip[J]. Progress in Biochemistry and Biophysics,2000,27(3):251-254
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