In order to arrive at a complete description and understanding of brain function and anatomy, the neuroimaging techniques are required to provide both high temporal resolution and high spatial resolution. Multimodal imaging that combining hemodynamic and electrophysiological information (i.e., fMRI/PET and EEG/MEG), holds promise for imaging patterns of human brain activity in both space and time. Multimodal imaging has succeeded in revealing the spatiotemporal pattern of brain activity underlying selective attention, visual perception of kinetic form, voluntary movement and semantic processing. However, there are still much work to do to improve the accuracy and the spatiotemporal resolution of multimodal imaging to elucidate the neural mechanisms of human cognition.